DWI在正常前列腺及前列腺疾病的初步应用  

Diffusion-weighted imaging in normal prostate and differential diagnosis of prostatic diseases

作　　者：任静[1] 宦怡[1] 常英娟[1] 赵海涛[1] 葛雅丽[1] 刘燕丽[1] 魏光全[1] 张劲松[1] 徐俊卿[1] 

机构地区：[1]第四军医大学西京医院放射科,陕西西安710032

出　　处：《中国医学影像技术》2007年第5期748-751,共4页Chinese Journal of Medical Imaging Technology

摘　　要：目的研究正常前列腺、前列腺癌(PCa)、良性前列腺增生(BPH)和前列腺囊肿的DWI表现及其ADC值的变化特点,探讨DWI在前列腺疾病诊断和鉴别诊断的应用。方法分别对16名健康志愿者,9例前列腺囊肿,29例BPH和21例PCa患者进行前列腺DWI扫描,分析正常前列腺中央带、外周带、囊肿、前列腺增生结节以及前列腺癌灶的DWI表现、ADC值的变化特点及其在诊断和鉴别诊断的价值。所有BPH和PCa病例均经病理证实。结果DWI表现:16名志愿者外周带信号高于中央带,二者分界清晰;囊肿呈高信号;BPH增生结节信号不均匀,信号强度低于外周带;PCa表现为低信号影。各组平均ADC值:正常前列腺中央带(1.352±0.052)×10-3mm2/s,外周带(1.829±0.071)×10-3mm2/s,囊肿(2.557±0.084)×10-3mm2/s,BPH增生结节(1.576±0.101)×10-3mm2/s,PCa癌灶(0.934±0.166)×10-3mm2/s,其ADC值由高到低依次为前列腺囊肿、正常外周带、BPH、正常中央带和PCa癌灶(P=0.000)。结论DWI及ADC值在一定程度上有助于正常前列腺、前列腺囊肿、BPH和PCa之间的鉴别。Objective To investigate the DWI appearance and the ADC value of the normal prostate gland, cyst of pros tate, benign prostatic hyperplasia （BPH） and prostatic carcinoma （PCa）, and to evaluate the value of DWI in the diagnosis and differential diagnosis of prostatic diseases. Methods Sixteen healthy volunteers, 9 prostate cysts, 29 BPH and 21 PCa were scanned with DWI respectively. Their DWI and ADC characteristics were analyzed and the diagnositic and differential diagnositic values of DWI and ADC were summarized. All the BPH and PCa received a histological diagnosis. Results DWI appearance., the central zone and peripheral zone of normal prostate were shown clearly. The signal intensity of BPH nodule was nonuniform and lower than the peripheral zone. PCa showed very low signal intensity while the prostate cyst showed high signal intensity. The mean ADCs for the normal central gland, peripheral zone, cyst of prostate, BPH nodules and PCa focus were （1. 352±0.052）×10^-3 mm^2/s, （1. 829±0.071）×10^-3 mm^2/s, （2. 557±0. 084）×10^-3 mm^2/s, （1. 576±0. 101）× 10^-3 mm^2/s and （0. 934±0. 166） ×10^-3 mm^2/s respectively （P=0. 000）. Conclusion The DWI appearance and ADCs for the normal central gland, peripheral zone, cyst of prostate, BPH nodules and PCa demonstrate a significant difference, and that can be used＇in the diagnosis and differential diagnosis of the diseases of prostate.

关 键 词：前列腺肿瘤 前列腺增生 前列腺囊肿 扩散加权成像 

分 类 号：R697.3[医药卫生—泌尿科学] R445.2[医药卫生—外科学]