严重药物不良事件对住院时间和费用的影响分析  

Influence of Time and Costs of Hospitalization by Severe Adverse Drug Events

作　　者：翟晓波[1] 鲍思蔚[1] 王海平[1] 何志高[1] 

机构地区：[1]上海市同济大学附属东方医院药剂科,上海200120

出　　处：《药物流行病学杂志》2007年第3期153-156,共4页Chinese Journal of Pharmacoepidemiology

基　　金：本研究受2006年上海市卫生局科研项目资助(课题编号:2006087)

摘　　要：目的:初步调查某院呼吸内科和消化内科病房严重药物不良事件(ADEs)与住院时间延长、经济负担加重的关系。方法:药师深入病房。集中监测ADEs,主要监测内容是严重ADEs的存在与否,可否防范,并统计使住院时间延长、加重经济负担的量化指标。结果:在呼吸内科8个月、消化内科5个月期间,共鉴定严重ADEs20例,每例平均使住院时间延长了17.8d,住院费用增加了16869元;其中有11例可预防,每例平均使住院时间延长了19.3d,住院费用增加了12578元。结论:严重ADEs可显著延长住院时间,加重经济负担。其中有相当一部分可防范,采取有效措施降低其发生率意义重大。Objective： To study the relations between the length and costs of hospitalization and the severe adverse drug events which took place in the gastroenterologic and pulmonary wards. Method： Pharmacists surveyed ADEs including their existence and preventability in the wards, and found out the quantity of excessive length and extra costs of hospitalization. Result： There were totally 20 identified severe ADEs in which 11 were preventable in the pulmonary wards during 8 months and in the gastroenterologic wards during 5 months. The mean attribute length of stay was 17.8 days and mean attribute extra cost of hospitalization was 16,869 yuan for each ADE. The mean attribute length of stay was 19.3 days and mean attribute extra cost of hospitalization was 12,578 yuan for each preventable ADE. Conclusion： The attribute length of stay and extra costs of hospitalization were substantial. Since many severe ADEs were preventable, the effective measure must be taken to decrease their incidence.

关 键 词：严重药物不良事件 防范 住院时间 住院费用 

分 类 号：R969.2[医药卫生—药理学]