盐酸硫必利硬膜外自控镇痛效果观察  

Tiapride used in patient-controlled postoperative epidural analgesia

作　　者：周齐鸣[1] 

机构地区：[1]成都市第三人民医院麻醉科,四川成都610031

出　　处：《实用医院临床杂志》2007年第4期53-54,共2页Practical Journal of Clinical Medicine

摘　　要：目的对比盐酸硫必利与阿片类药物用于硬膜外镇痛的效果及不良反应。方法40例ASAⅠ～Ⅱ级患者,术后均行硬膜外自控镇痛,A组20例,用哌替啶250mg+0.125%布比卡因,总量150ml;B组20例,用盐酸硫必利0.5g+0.125%布比卡因,总量150ml。结果两组镇痛效果比较差异无显著性意义(P>0.05);不良反应A组高于B组,差异有显著性意义(P<0.05)。结论盐酸硫必利用于硬膜外镇痛时不良反应发生率明显低于阿片类组。Objective To compare the analgesic effect and side effect between Tiapride and opioids in epidural analgesia. Methods Forty ASA Ⅰ -Ⅱ patients undergoing epidural anesthesia and postoperative epidural analgesia were randomly divided into two groups. In Group A （ n ：=20） , pethidine 250 mg plus 0. 125% bupivacaine with the total volume of 150 ml was used. In Group B （n = 20） , Tiapride 0. 5 g plus 0. 125% bupivacaine with the same volume as Group A was used. Results There was no significant difference in analgesic effect between the two groups. The rate of side effect was significantly higher in Group A than Group B （ P 〈 0. 05 ）. Conclusion The rate of side effects of Tiapride is significantly lower than that of opioids when used in epidural analgesia.

关 键 词：盐酸硫必利 阿片类药物 硬膜外自控镇痛 

分 类 号：R614.42[医药卫生—麻醉学]