云南省某市女性性工作者HIV感染及其危险因素调查  

Prevalence and risk factors associated with HIV infection among female sex workers in a county of Yunnan province

作　　者：汪海波[1] 汪宁[1] 丁国伟[1] 马建国[2] 王桂香[2] 陆林[3] 马艳玲[3] 徐俊杰[1] 常东方[2] 张国磊[1] 张斓[1] 董瑞玲[1] 乌正赉[4] 郑锡文[1] 

机构地区：[1]中国疾病预防控制中心性病艾滋病预防控制中心,北京100050 [2]开远市疾病预防控制中心,云南开远661600 [3]云南省疾病预防控制中心,昆明650022 [4]中国协和医科大学,北京100730

出　　处：《中国艾滋病性病》2007年第3期220-223,共4页Chinese Journal of Aids & STD

基　　金：美国国立卫生院资助CIPRA项目(NIHCH005);科技部资助国家"十五"攻关项目(2004BA719A02)

摘　　要：目的了解云南省某市女性性工作者(FSWs)艾滋病病毒(HIV)和性传播疾病(STD)的感染情况及HIV感染相关危险因素。方法招募FSWs调查其一般人口学及行为学资料,采集静脉血进行HIV、单纯疱疹病毒2型(HSV-2)和梅毒血清学检测,采集尿液进行尿吗啡检测,采集宫颈分泌物进行淋球菌和沙眼衣原体检测,采集阴道分泌物进行阴道毛滴虫检测。结果共收集血液标本737份,其中76份经确认为HIV抗体阳性,感染率为10.3%,梅毒感染率为7.5%,HSV-2感染率为68.1%。共收集阴道和宫颈分泌物标本各737份,淋病感染率为8.3%,沙眼衣原体感染率为25.9%,阴道毛滴虫感染率为10.6%。共收集尿标本739份,吗啡阳性率为15.6%。多因素logistic回归模型分析显示,与HIV感染有关的危险因素是:低档性服务场所服务,静脉注射吸毒,过去一年出现下腹部疼痛,生殖器溃疡,外阴增生物,从事性服务时间≥5年,HSV-2阳性。结论当地FSWs的HIV和STD感染率较高,需针对该人群采取有效的干预措施,及时治疗STD,控制HIV的传播流行。Objective To explore the epidemiological features of infections of HIV, syphilis, Gonorrhoea, Chlamydia trachomatis, vaginal trichomoniasis and HSV-2 among female sex workers（FSWs）in Yunnan province and to identify risk factors associated with HIV infection. Methods FSWs were recruited to investigate their demographic information, drug use and sexual behavior, HIV/AIDS related knowledge and reproductive health status. Venous blood specimens were collected to test HIV,HSV-2 and syphilis. Urine specimens were collected to test morphine,cervical secretions were collected to test Gonorrhoea and Chlamydia trachomatis, and vaginal secretion was collected to test Trichomonas vaginalis. Results A total of 737 blood specimens were collected,in which 76 specimens were confirmed to be HIV positive, and the HIV prevalence was 10.3 % ; the prevalence of syphilis and HSV-2 was 7.5 %, and 68.1%, respectively. A total of 737 vaginal and cervical secretion specimens were collected, in which the prevalence of Gonorrhoea, Chlamydia and Trichomonas was 8.3 % ,25.9 % and 10.6 %, respectively. A total of 739 urine specimens were collected, in which the morphine positive rate was 115.6 %. As shown by the multivariate logistic analysis, the factors associated with HIV infections were：engagement in sex activities in low level entertainment locations, intravenous drug users （IDU）, illegal drug abuse（ non-IDU）, emerging hypogtric pain or genital ulcer of warts in the last year, engagement in sex work≥5 years and HSV-2 positive status.Condusion The prevalence of HIV and STD is comparatively high among local FSWs,for whom effective interventions for STD are urgently needed so that they could be timely treated and HIV epidemic be controlled.

关 键 词：女性性工作者 艾滋病病毒 静脉注射 安全套 

分 类 号：R512.91[医药卫生—内科学]