直肠癌组织与直肠正常组织的荧光光谱研究  

Investigation on the Fluorescence Spectroscopy of Normal and Malignant Rectum Tissues

作　　者：孟涛[1] 徐端夫[1] 徐怡庄[2] 赵莹[1] 王笃金[1] 吴瑾光[2] 

机构地区：[1]中国科学院化学研究所高分子物理与化学国家重点实验室,北京100080 [2]北京大学化学与分子工程学院,北京100871

出　　处：《光谱学与光谱分析》2007年第6期1156-1160,共5页Spectroscopy and Spectral Analysis

基　　金：国家重点基础研究发展规划项目(2002CCA01900);国家自然科学基金项目(30371604)资助

摘　　要：用荧光光谱仪对12例离体直肠癌组织和对应的直肠正常组织的荧光光谱(激发光的波长为320nm)进行了研究。并与相应的红外光谱结果进行了对比。结果表明直肠正常组织的荧光强度明显高于直肠癌组织的荧光强度。直肠组织在波长为492和544nm的荧光强度的差别可用于区分直肠正常和直肠癌组织。In the present article the fluorescence characteristics of normal and malignant rectum organ tissues of 12 samples were investigated in vitro using UV （200-400 nm） fluorescence spectroscopy and compared with the results of the infrared spectra of normal and malignant rectum organ tissues. The results showed that the fluorescence intensity of normal rectal tissue was higher than that of rectal malignant tissue. The difference in fluorescence intensity at 492 and 544 nm between normal rectal tissue and malignant tissue may be considered as a detection criterion.

关 键 词：直肠癌 最佳激发波长 荧光光谱 诊断 

分 类 号：O657.3[理学—分析化学]