血清降钙素原在新生儿重症感染的诊断及其临床意义  

Clinical Significance of Procacitonin for Early Diagnosis in the Neonate with Septicemia and Purulent Miningitis

作　　者：郑洁[1] 李茹琴[1] 

机构地区：[1]大连市儿童医院,大连116012

出　　处：《中国现代医生》2007年第06X期5-6,共2页China Modern Doctor

摘　　要：目的评价PCT对新生儿败血症及颅内感染者早期诊断价值及其临床意义。方法抽取36例败血症患者外周血标本,同时做PCT-Q检测、普通血培养和CFS。结果36例败血症患者中5例血培养阳性(13.9%),其中CFS检测颅内感染者27例(75.0%),PCT-Q检测结果和CSF检测结果对比经χ2检验具有明显差异(χ2=11.5,P<0.01)。结论PCT-Q检验法较普通血培养法灵敏,对新生儿重症感染,特别是败血症及颅内感染者病因诊断具有指导意义。Objective To evaluate PCT clinical significance for the early diagnosis in the neonate with septicemia and purulent miningitis. Methods The blood samples of 36 eases with septicemia were drawn out for determining PCT-Q and blood culture.If results PCT is positive patients were engaged in lumbar puncture. Results The 5 eases were positive in with 36 eases septicemia （13.9%）,among 27 eases were diagnosised in determining CSF （75.0%）. There are significant difference between PCT-Q and CSF contract （ x^ 2=-11.5, P〈0.01）. Conclusion The method of PCT-Q was more sensitive and specific than blood culture. The method of PCT-Q is important guiding significance for the diagnosis of pathogens in the neonate with septicemia and purulent miningitis.

关 键 词：降钙素原 败血症 颅内感染 新生儿 

分 类 号：R722.13[医药卫生—儿科]