慢性阻塞性肺气肿并发急性呼吸衰竭经口／鼻面罩双水平气道正压通气治疗的临床探讨  

Treatment of Respiratory Failure Secondary to the Acute Exacerbation of Chronic Obstructive Pulmonary Diseases Through Bilevel Positive airway Pressur Eventilation Via Nasal/mouth Mask

作　　者：高爽[1] 何永红[1] 曾志伟[1] 

机构地区：[1]广州市白云区人民医院内科,广东广州510500

出　　处：《国际医药卫生导报》2007年第12期39-42,共4页International Medicine and Health Guidance News

摘　　要：目的 观察慢性阻塞性肺疾病合并Ⅱ型呼吸衰竭患者应用经口/鼻面罩双水平气道正压通气（BiPAP）呼吸机正压通气治疗的效果。方法 45例COPD急性发作并Ⅱ型呼吸衰竭患者随机分为两组,治疗组23例,采用BiPAP＋常规治疗,对照组22例,仅采用常规临床治疗,比较治疗前、治疗2h、24h后两组同期动脉血气及呼吸频率、心率改变。结果 治疗组PaO2、PaCO2、pH值较治疗前明显改善（P〈0.05）,改善与对照组比较,有显著性差异（P〈0.05）;呼吸频率、心率改变也较对照组明显（P〈0.05）。气管插管发生率及平均住院天数均少于对照组（P〈0.05）。结论 BiPAP是治疗慢性阻塞性肺气肿急性发作期并Ⅱ型呼吸衰竭经济、有效的方法。Objective To evaluate the clinical effectiveness by using bilevel positive airway pressure（BiPAP） ventilation via nasal/mouth mask in patients with respiratory failure secondary to the acute exacerbation of chronic obstructive pulmonary diseases （COPD）.Methods 23 patients were rangdomly submitted either to standard therapy plus BiPAP and 22 patients to standard therapy. Cliniacl manifestation（including respiratoryrate, heart rate, blood pressure and conscious status） and arterial blood gas analysis before and after 2hour, 24hour after treatment in each group were comparatively analyed. Results After treatment by BiPAP, patients showed a significant improvement in PaO2, PaCO2, and clinical manifestation, and there was a significant difference between two groups（P〈0.05）.Conclusion BiPAP ventilation is effective in patients with respiratory failure during acute exacerbation of COPD.

关 键 词：无创正压通气 慢性阻塞性肺气肿 呼吸衰竭 

分 类 号：R563[医药卫生—呼吸系统]