参麦注射液制备工艺研究  

Study on Preparing Technology of Shenmai Injection by Orthogonal Methods

作　　者：钟永红[1] 周南[1] 钱琳[1] 

机构地区：[1]湖南省人民医院,湖南长沙410005

出　　处：《中医药导报》2007年第6期106-107,共2页Guiding Journal of Traditional Chinese Medicine and Pharmacy

摘　　要：目的:研究参麦注射液的制备工艺,确定最佳工艺条件,提高产品收率。方法:采用L9(34)正交试验设计方法,对参麦注射液制备的反应条件进行优选,并采用HPLC法测定样品中人参皂苷Rb1的收率。结果:最佳工艺条件为煎煮时间1.5h,浓缩倍数1kg/L,101澄清剂(5%)添加量7%。结论:该方法可用于参麦注射液的工业化生产。Objective： To study the technique for preparation of Shenmai injection and select the best reacting conditions to increase the product yield. Methods： The optimum reaction conditions of Shenmai injection preparation were selected by orthogonal design method and the yield of ginsenosides Rbt in the samples was determined by HPLC. Results： The optimum reaction conditions were： the time of decoeting was 1.5 h; the multiplicity of concentrating is 1kg/L and the accession of 101clarifier （5%） was 7%. Conclusion： This technology of preparing Shenmai injection is available for industrial production.

关 键 词：参麦注射液 正交试验 制备工艺 

分 类 号：R944.11[医药卫生—药剂学]