Effect of ifenprodil pretreatment on the expression of NR2B subunit protein of NMDA receptor in the dorsal horn of spinal cord in a rat model of neuropathic pain  

作　　者：虞雪融 

机构地区：[1]Dept Anesthesiol, Peking Union Hosp, PUMC CAMS,Beijing 100730

出　　处：《China Medical Abstracts》2007年第2期91-91,共1页中国医学文摘（外科学分册英文版）

摘　　要：Objective To investigate the effect of ifenprodil pretreatment on the expression of NR2B subunit protein of NMDA receptor in the dorsal horn of spinal cord in a rat model of neuropathic pain. Methods Fifty male SD rats weighing 180-200 g were used in this study. Neuropathic pain was produced by chronic constrietive injury （CCI）. The left sciatic nerve was exposed and 4 loose ligatures were placed on the sciatic nerve at 1-2 mm intervals with 4-0 chromic catgut under pentobarbital anesthesia.

关 键 词：艾芬地尔 神经痛 脊椎麻醉 NR2B 

分 类 号：R614[医药卫生—麻醉学]