Analgesic effect of intrathecal fluorocitrate on neuropathic pain in rats  

Analgesic effect of intrathecal fluorocitrate on neuropathic pain in rats

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作  者:孙涛 

机构地区:[1]Dept Anesthesid, Union Hasp, Tongji Med Col Huazhong Univ Sci Technol, Wuhan 430022

出  处:《China Medical Abstracts》2007年第2期92-92,共1页中国医学文摘(外科学分册英文版)

摘  要:Objective To investigate the analgesiac effect of intrathecal (IT) fluorocitrate (FC) ( a selective astrocyte metabolic inhibitor) on neuropathic pain induced by chronic constrictive injury (CCI) to sciatic nerve. Methods Thirty- two adult male SD rats weighing 220-280 g were randomly divided into 4 groups ( n = 8each) : group A sham operation+ (IT) vehicle; group B sham operation + (IT) FC;group C CCI+ (IT) vehicle and group D CCI+ (IT) FC.

关 键 词:神经痛 氟代柠檬酸 止痛效果 药品 

分 类 号:R98[医药卫生—药品]

 

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