二茂铁甲酸的合成  

Synthesis of ferrocenecarboxylic acid

作　　者：王世辉[1] 洪秀云[1] 孙蕊[1] 金丽萍[1] 胡春[1] 

机构地区：[1]沈阳药科大学制药工程学院,辽宁沈阳110016

出　　处：《应用化工》2007年第6期540-541,共2页Applied Chemical Industry

基　　金：国家自然科学基金资助项目(20472053)

摘　　要：在三氯化铝催化下,以二茂铁和邻氯苯甲酰氯反应,合成了邻氯苯甲酰二茂铁,然后用异丙醇铝裂解邻氯苯甲酰二茂铁得到二茂铁甲酸,其结构经IR和1H NMR确认。该方法用廉价的异丙醇铝代替叔丁醇钾,降低了成本。Ferrocenecarboxylic acid ,2-chlorobenzoylferrocene was synthesized by the reaction of ferrocene and 2-chlorobenzoylchloride, aluminum trichloride as the catalyst, then ferrocenecarboxylic acid was pre- pared by the reaction of 2-chlorobenzoylferrocene and aluminum isopropoxide. Its structure was characterized by IR and ^1H NMR. The replacement of potassium tert-butoxide with aluminum isopropoxide result in cost reduction in preparation of ferrocenecarboxylic acid.

关 键 词：二茂铁甲酸 邻氯苯甲酰二茂铁 异丙醇铝 

分 类 号：O627.8[理学—有机化学]