丙三醇壳聚糖的制备与分析  

The Preparation and Analysis of Glycerolchitosan

作　　者：王爱勤[1] 李洪启[1] 张俊彦[1] 俞贤达[1] 

机构地区：[1]中国科学院兰州化学物理研究所,兰州730000

出　　处：《中国生化药物杂志》1997年第2期75-77,共3页Chinese Journal of Biochemical Pharmaceutics

基　　金：甘肃省科学基金;中国科学院兰州化学物理研究所所长择优基金

摘　　要：用3-氧-1，2-丙二醇对壳聚糖进行了化学改性，并用红外光谱和X-衍射产物进行了结构表征，其反应主要发生在-NH2基团上，产物在许多有机溶剂中的溶解性有明显改善。The modification of chitosan by 3-chloropropane-1, 2-diol was studied. The structure of glycerolchitosan was characterizated using IR spectroscopy and X-ray. The results are consistent with N-substituted prior to that C6 position. The solubility of glycerolchitosan in many organic solvents was enhaned compared with that of chitosan.

关 键 词：壳聚糖 丙三醇壳聚糖 红外光谱 制备 药物缓释 

分 类 号：TQ460.4[化学工程—制药化工] O636.1[理学—高分子化学]