外伤复明胶囊对血小板粘附功能和血栓形成影响的实验研究  

A study on the effect of waishang fuming capsule in thrombosis and function of thrombocyte adhesion

作　　者：万素君[1] 郑君[1] 毛艳英 吴广军[1] 

机构地区：[1]中国中医研究院广安门医院基础室,北京100053

出　　处：《中国中医眼科杂志》1997年第2期74-76,共3页China Journal of Chinese Ophthalmology

基　　金：国家中医药管理局科研基金

摘　　要：目的：观察外伤复明胶囊对实验动物血栓形成及血小板粘附功能的影响。方法：分别进行小鼠抗体内血栓形成实验、家兔抗体外血栓形成实验和大鼠抗血小板粘附实验。结果：外伤复明胶囊对小鼠体内血栓形成致死抑制率为30％～40％；抗家兔体外血栓形成作用优于丹参对照组；抗大鼠血小板粘附作用低于丹参对照组。结论：外伤复明胶囊有抑制实验动物血栓形成和抗血小板粘附作用。OBJECTIVE: To investigate the effect of waishang fuming capsule in experimentalthrombosis and function of thrombocyte adhesion. METHODS: Mice anti-thrombotic experiments in vivo, rabbit anti-thrombotic experiments in vitro and rat anti thrombocyte adhesion ex-periments were performed respectively. RESULTS: The repression rate of waishang fuming capsule for the mice fatality due to thrombosis was in vivo 30% ~ 40%. The anti-thrombotic effect ofwaishang fuming capsule for rabbit in vitro was better than in salvia miltiorrhiza control group.The anti-thrombocyte adhesion effect of waishang fuming capsule in rat was lower than in salviamiltiorrhiza control group. CONCLUSION: Waishang fuming capsule has effect ofanti-thrombotic and anti- thrombocyte adhesion in experimental animals.

关 键 词：外伤复明胶囊 血小板粘附 血栓形成 实验药理学 

分 类 号：R287.81[医药卫生—中药学]