进驻海拔5,380m不同时间的青年人血液流变性和RBC-SOD的变化  

The change of blood rheological property and RBC-SOD on youth who are garrisoned to regions 5380m above sea level at different time

作　　者：张西洲[1] 何富文[1] 张新宇[1] 王伟[1] 马勇[1] 张素萍[1] 

机构地区：[1]解放军第18医院

出　　处：《西藏医药》1997年第3期8-10,共3页Tibetan Medicine

摘　　要：本文对进驻海拔5，380m第3天、第25天、第4个月，第11个月的20名青年血液流变性和RBC－SOD进行了随访调查，并与进驻高原前作对照，结果：随进驻高原时间的延续，HCT、ηb、PFc、TK、MST、TFL递增，RBC－SOD递减（P＜0．01或P＜0．05）。作者认为缺氧引起HCT增高是血液粘度增高的重要因素；缺氧引起ATP生成减少和红细胞内液粘度增高是红细胞变形能力降低的主要原因。高原低氧环境使体内自由基生成增多，SOD活性降低。Follow - up survey of blood rheological property and RBC-SOD were made among 20 young people who are garrisoned to regions 5380m above sea level on the 3rd day, the 25th day, the 4th month, the 11thmonth; and compared with those records before garrison. The result shows that following the garrison time prolonged in altitude,HCT. 3b. PFC. TK. MST. TFL increased progressively, RBC - SOD decreaseu progressively (p < 0.01 or p <0.05 ). The writer considers that increasilig of HCT cau sed by hypoxia is an important factor ofblood viscosity increasing; ATP formation decreasing and internal fluid viscosity of RBC increasing caused by hypoxia is the main cause of decreasing of RBC distortion ability;altitude hypoxia environment caused inner - body free radical formation increasing and SOD activity decreasing.

关 键 词：高原 血液流变学 超氧化物歧化酶 

分 类 号：R594.3[医药卫生—内科学]