硝基苯对小鼠急性毒性试验的研究  

Effect of NB on acute toxicity in mice

作　　者：邢厚娟[1] 王海波[1] 王敏[1] 徐世文[1] 

机构地区：[1]东北农业大学动物医学院,哈尔滨150030

出　　处：《东北农业大学学报》2007年第3期380-383,共4页Journal of Northeast Agricultural University

基　　金：黑龙江省教育厅资助项目(YJSCX2007-0043HLJ)

摘　　要：用Weil's表的平均移动法进行了NB对雌性小鼠和雄性小鼠LD_(50)的测定。以组间距(对数剂量差值)为d=0.2,测得NB对雄性小鼠经口服的LD_(50)为525.8962mg·kg^(-1)BW,95%可信限为417.7342～662.0640mg·kg^(-1)BW;以组间距(对数剂量差值)为d=0.0667,测得NB对雌性小鼠经口服的LD_(50)为771.9692mg·kg^(-1)BW,95%可信限为714.8254～833.6812mg·kg^(-1)BW。Using the mean motion method of Weil＇s table to determine the LD50 of the female mouse and male mouse induced by NB. The group spacing （logarithm dosage difference） was d=0.2, and the oral LD50 of the male mouse induced by NB was 525.8962 mg·kg^-1 BW, 95% confidence limit was 417.7342-662.0640 mg·kg^-1 BW; the group spacing （logarithm dosage difference） is d=0.0667, and the oral LDso of the female mouse induced by NB was 771.9692 mg·kg^-1 BW,95% confidence limit was 714.8254-833.6812 mg·kg^-1 BW.

关 键 词：硝基苯 急性毒性 小鼠 LD50 

分 类 号：TQ086.5[化学工程] S994.6[农业科学—水产科学]