超声造影定性诊断肝脏局灶性病变  

Qualitative diagnostic value of liver focal lesions by using contrast enhanced ultrasound

作　　者：汤庆[1] 周大治[1] 廖海星[1] 叶素敏[1] 许峭峰[1] 袁敏翰[1] 黄帼英[1] 陈毓菁[1] 

机构地区：[1]广州医学院第一附属医院超声科,510120

出　　处：《现代临床医学生物工程学杂志》2006年第5期399-401,共3页Journal of Modern Clinical Medical Bioengineering

基　　金：广东省自然科学基金资助项目(06301115)

摘　　要：目的探讨超声造影对肝脏局灶性病变的增强表现及定性诊断价值。方法使用SonoVue造影剂和低机械指数实时造影成像CnTI技术,对经超声检出的90个肝局灶性病变进行超声造影。研究病灶的造影增强模式,并与手术、病理、或增强CT及MRI结果比较。结果CnTI技术显示肝内良、恶性病灶具有不同的增强模式和特征。(1)恶性病灶:原发性肝细胞癌(HCC)25灶,23个呈“快进快出”,2个为“快进慢出”不典型表现;转移性肝癌18灶,动脉期呈周边环状或厚圈状“快进”,之后均廓褪为低或极低回声(黑洞)。(2)良性病灶大多数表现为“慢出”模式,其中肝血管瘤多为典型“慢进慢出”。(3)恶性病灶的诊断敏感性、特异性、准确性分别为95.3%、89.4%、89.1%。结论超声造影定性诊断肝内局灶性病变的准确率高,具有很好的应用前景。Objective To evaluate the accuracy of pattern-based of contrast enhanced ultrasound and qualitative diagnosis in liver focal lesions. Methods After injection of contrast ultrasound agent--SonoVue, 90 hepatic lesions were scanned with CnTI US and compared with surgery, pathology, enhanced CT and MRI. Results There were different enhancement patterns in malignant tumor and benign tumor. In hepatocellular carcinoma （ n = 25 ）, the presence of swift enhancement in the arterial phase and swift expurgation in the portal phase were the most typical patterns. In metastases （n = 18 ）, the ring enhancement or a perfusion defect were the most typical patterns. In benign tumor, the slow expurgation was the most typical pattern. The sensitivity, specificity and accuracy of diagnosis for malignant tumor were 95.3 % ,89.4 % and 89.1% respectively. Conclusion The qualitative diagnosis by using contrast ultrasound on liver focal lesions presents higher accuracy with a good prospect.

关 键 词：超声 造影剂 肝肿瘤 诊断 

分 类 号：R445.1[医药卫生—影像医学与核医学]