山东省班氏丝虫病传播阈值的研究  

STUDY ON THE TRANSMISSION THRESHOLD OF BANCROFTIAN FILARIASIS IN SHANDONG PROVINCE

作　　者：王培义[1] 尹舜[1] 高长兰[1] 盛琦[1] 赵中平[1] 李登俊[1] 曹新春[1] 刘伦华[1] 万功群[1] 刘波[1] 公茂庆[1] 刘新[1] 张佃波[1] 王洪法[1] 

机构地区：[1]山东省寄生虫病防治研究所

出　　处：《中国寄生虫病防治杂志》1997年第1期11-15,共5页Chinese Journal of Parasitic Disease Control

摘　　要：在鲁南原班氏丝虫病高度流行区的郯城县胜利乡花园村，于基本消灭后第５年（１９８４）开始，在不采取防治措施的情况下，纵向观察１０年，微丝蚴率由观察前的０．５６％降至０．１２％，观察前９例残存微丝蚴血症者，其中有８例陆续自然转阴。原残存微丝蚴血症者第１０年检测血中ＩｇＧ４抗体转阴率为８８．８９％。蚊媒自然感染率１９８４～１９８６年分别为０．２１％、０．１９％和０．０６％，第１０年（１９９３年）未再发现蚊媒幼丝虫。年传播潜势由３．４７降到０。结果表明，在当地自然环境条件下，蚊媒密度以人饵诱捕法调查不用蚊帐人群叮人率为２４．１～５２．５只／人·夜，使用蚊帐人群叮人率为１３．５～２１只／人·夜，居民微丝蚴率为０．５６％及残存微丝蚴血症者６０μｌ血微丝蚴平均密度为６．６～２０．７条的情况下，班氏丝虫病处于传播阈值以下，居民微丝蚴率逐步降低，趋于终止传播。In order to explore the transmission dynamic state and epidemic trend of bancroftian filariasis after its basic eradication, a 10 year longitudinal observation was conducted during the period of 1984(5 years after the basic eradication) to 1993 in Huayuan village,Shengli township of Tancheng conuty in the southern Shandong province of the previous highly endimic area. The microfilaremia rate was found to have dropped from 0.56% before the observation to 0.12% after it. Eight out of the nine microfilaria carriers detected before the observation and five out of the six detected after the observation became negative naturally respectively. The natural negative conversion rate of IgG4 in the former microfilaria carriers was 88.89%. The natural infection rate of mosquito vectors dropped year by year, with no mosquito found with filarial larvae in the 10th year (1993). Annual transmission potential dropped from 3.47 to 0. The results showed that when no control measures was taken,the mosquito biting rates for those not using net and those not using were 24.1～52.5/person/night and 13.5～21/person/night,respectively. The transmission of filariasis was below the transmission treshold and very close to the end of transmission.

关 键 词：丝虫病 传播阈值 班氏丝虫病 低密度 微丝蚴血症 

分 类 号：R532.15[医药卫生—内科学]