南京地区成人代谢综合征的流行病学研究  

Epidemiological study of metabolic syndrome in Nanjing district

作　　者：冯雨[1] 唐伟[1] 喻荣彬[2] 段宇[1] 茅晓东[1] 刘超[1] 

机构地区：[1]南京医科大学第一附属医院内分泌科,江苏南京210029 [2]南京医科大学公共卫生学院,江苏南京210029

出　　处：《南京医科大学学报（自然科学版）》2007年第7期773-776,共4页Journal of Nanjing Medical University(Natural Sciences)

基　　金：江苏省政府医学重点学科资助项目(2001-34)

摘　　要：目的:了解南京地区社区人群代谢综合征(metabolic syndrome,MS)的患病率及流行特征。方法:采用分层随机整群抽样方法调查南京两社区20岁及20岁以上的常住(>5年)居民共1130人(男400人,女730人),进行问卷调查、体格检查及相关代谢指标的测定。MS主要采用2005年国际糖尿病联盟(IDF)的诊断标准。结果:南京地区成人总人群、男性及女性MS的粗患病率分别为19.3%、12.8%和22.9%。相应的标化患病率分别为13.1%、9.2%和15.2%。女性患病率显著高于男性(P<0.05)并随年龄的增长而显著升高(P<0.05);血压升高(≥130/85mmHg)、甘油三酯(TG)升高、空腹血糖升高、高密度脂蛋白(HDL)降低在MS患者中的发生率分别为89.9%、65.6%、29.4%及71.1%。MS患者中仅有2个代谢异常的占51.8%,有3个组分异常的占40.4%,而4个组分均异常的占7.8%;结论:南京地区成年人群MS患病率较高,女性、老年人是MS的高危人群,加强健康宣教十分重要。MS患者中高血压最常见,其他代谢异常的患病率也较高,应全面地进行防治。Objective：To describe the prevalence rate of metabolic syndrome （MS） in Nanjing district. Methods： 1 130 residents from two districts of Nanjing, who had lived for at least five years and more than 20 years old, were enrolled in this survey. Fasting plasma glucose, triglycerides （TG）, high density lipoprotein-C （HDL-C） were measured. Results：The crude prevalence of MS were 19.3%, 12.8%, 22.9% in total population, male and female respectively while the standardized rate were 13.1%, 9.2%, 15.2% accordingly. Female and aged people was the population at high risk of MS. The prevalence of hypertension （≥ 130/85 mmHg）, hypertriglyceridemia, abnormal fasting plasma glucose, hypoalphalipoproteinemia-C were 89.9%, 65.6%,29.4%, 71.1% respectively among MS individuals, of which 51.8% incorporated only two metabolic abnormities, 40.4% incorporated three metabolic abnormities and 7.8% had four metabolic abnormities. Conclusion：The prevalence rate of MS in Nanjing was very high. Old and female people were at higher risk. Hypertension was the most frequent metabolic abnormity among MS individuals and the prevalence of other metabolic abnormities were also very high.

关 键 词：代谢综合征 中心性肥胖 高血压 血脂紊乱 患病率 

分 类 号：R181.32[医药卫生—流行病学]