女性护骨素基因启动子区G209A与T245G多态性和骨密度及骨转换的关系  

Association of G209A and T245G polymorphisms of osteoprotegerin gene promoter with bone mineral density and bone turnover in females

作　　者：单鹏飞[1] 伍贤平[1] 张红[1] 罗湘杭[1] 曹行之[1] 刘石平[1] 谢辉[1] 陈志衡[1] 钟妮[1] 廖二元[1] 

机构地区：[1]中南大学湘雅二医院代谢内分泌研究所

出　　处：《中华内分泌代谢杂志》2007年第3期228-230,共3页Chinese Journal of Endocrinology and Metabolism

基　　金：卫生部临床学科重点项目(20012738)

摘　　要：研究护骨素基因启动子区G209A与T245G多态性和女性骨密度及骨转换生化指标的关系,结果显示G209A与T245G多态性和骨密度及骨转换生化指标无关。Relationships of osteoprotegerin gene promoter G209A and T245G polymorphisms with bone mineral density （BMD） and levels of bone turnover markers were observed in females. Results show that neither of the polymorphism are related to BMD and levels of bone turnover markers.

关 键 词：护骨素 多态现象 遗传 骨密度 骨转换 

分 类 号：R580[医药卫生—内分泌]