^(32)P-胶体治疗色素沉着绒毛结节性滑膜炎的体会  

Treatment of the Pigmented villonodular synovitis with the colloid of P^(-32)

作　　者：杜建强[1] 欧顺云[2] 陈松华[1] 朱丽娟[1] 赵娴[1] 

机构地区：[1]广州中医药大学附属第二医院核医学科,510120 [2]中山大学公共卫生学院,广州510089

出　　处：《影像诊断与介入放射学》2007年第3期138-139,共2页Diagnostic Imaging & Interventional Radiology

摘　　要：目的探讨32P-胶体治疗色素沉着性绒毛结节性滑膜炎在临床上的应用价值。方法门诊及住院病人12例,均为膝关节的色素沉着性绒毛结节性滑膜炎,在抽取关节液后,腔内注射胶体磷酸铬(Cr32PO4)5mCi。注射后嘱病人平卧,并变换体位。治疗前查血常规1次,治疗1个月内每周复查血常规,以后每月复查1次￣6个月。单纯手术组22例,2组病例随访观察疗效。结果所有病例无异常反应,追踪最长达24个月,病人无复发,血常规无异常,治愈率达100%,单纯手术组追踪1年以上,有7例复发,治愈率仅为68.2%。结论腔内注射胶体磷酸铬治疗膝关节的色素沉着性绒毛结节性滑膜炎是一种非常有效、安全的治疗方法,值得预以推广普及。Objective To analyze the value of colloid P-^32 in the treatment of Pigmented viilonodular synovitis （PVS）. Method 12 cases of knee PVS received the treatment with colloid P-^32 2 After drawing the fluid from the joint cavity, the colloid of P-^32 5mCi was injected into the cavity then the patients were asked to lie down 40 min, and to change position every 10 min. Blood routine was examined before and once a week after the therapy in the first month and then once a month in the following 6 months. 22 cases received operation. All the patients were follow-up. Result There is no side reaction and the blood routine was normal in the follow-up. The cure rate was 100% in colloid P-^32 treatment group. However, 7 cases of PVS recurred and the cure rate was 68.2% in operation treatment group. Conclusion The injection of P-^32 colloid in the cavity of knee joint to treat the PVS is safety and effective.

关 键 词：色素沉着性绒毛结节性滑膜炎 ^32 P胶体 放射性核素 

分 类 号：R686.7[医药卫生—骨科学]