烧伤后侵袭性感染和多器官功能不全综合征  

Invasive infection and multiple organ dysfunction syndrome(MODS)in burns

作　　者：张明良[1] 张普柱[1] 汪洋[1] 徐军[1] 张国安[1] 陈旭[1] 

机构地区：[1]北京积水潭医院烧伤科,100035

出　　处：《中华整形烧伤外科杂志》1997年第3期191-194,共4页

摘　　要：总结了158例烧伤侵袭性感染与多器官功能不全综合征(MODS)的关系。侵袭性感染导致MODS 有几个特点:①MODS 发病率高,达到81.6%,每例有平均2.73个器官发生功能不全。②MODS发展成 MOF 的发生率也高,约为50%。③MODS 死亡率低,而发展到 MOF 死亡率明显上升,达到90%以上。不同菌种感染中,G^+菌致器官功能不全(OD)发生率较低,G^-菌致 OD 发生率较高,而绿脓杆菌致OD 发生率最高,后果最严重。对发病机制及防治问题进行了讨论,认为由于发病机理尚未充分了解,针对机制的有效治疗缺乏,因此防治的主要手段仍是去除诱因,即控制侵袭性感染。一旦感染发生,则要保护好各个脏器,使 OD 不致发展成器官衰竭。The article analysed the relationship between invasive infection and MODS in 158 burned cases.The characteristics in MODS following invasive infection are presented.①Morbidity of MODS is high,it reaches 81.6%.②MODS may become progressive MOF,the possibility is 50%.③Death is as- sociated with MOF,rather than by MODS.Mortality of MOF is very high,it is over 90%.Among vari- ous microbes it is Pseudomonas pyocyanea that causes highest morbidity of MODS.The mechanism of MODS is complex and not fully understood.The treatment of MODS is difficult,so it is essential to con- trol invasive infection.In case of severe infection,protection of each organ is very important in order to avoid organ dysfunction progressing to organ failure.

关 键 词：感染 烧伤 多器官衰竭 

分 类 号：R644[医药卫生—外科学]