不同剂量生脉注射液与5%葡萄糖注射液配伍的稳定性研究  

Compatibility of Different Dosages of Shengmai Injection Mixed with 5% Glucose Injection

作　　者：马玉蓉[1] 许群芬[2] 

机构地区：[1]重庆市第五人民医院,重庆400064 [2]四川大学华西第二医院,四川成都610041

出　　处：《中国药业》2007年第14期29-29,共1页China Pharmaceuticals

摘　　要：目的考察不同剂量的生脉注射液与5%葡萄糖注射液配伍后配伍液的稳定性。方法将生脉注射液与5%葡萄糖注射液分别按10∶250,20∶250,30∶250,40∶250,50∶250,60∶250(v/v)的比例混合后,检查配伍液的不溶性微粒、pH值。结果随着配伍比例的增加,配伍液pH值无显著差异(P>0.05),但不溶性微粒显著增加(P<0.05)。结论临床应用时,应重视生脉注射液与5%葡萄糖注射液的配伍比例。Objective To observe the stability of the compatibility of Shengmai injection in ditterent concentrations with 5% glucose injection. Methods The pH and insoluble particles of the mixed solution were detected after Shengmai injection in different concentrations and 5% glucose injection were mixed（10 ： 250, 20 ： 250, 30 ： 250, 40 ： 250, 50 ： 250, 60 ： 250）. Results The pH of the mixed solution showed no significant changes after mixed（ P 〉 0. 05）, however the insoluble particles in the mixed solution increased significantly（P 〈 0. 05）with the contents increase of Shengmai injections. Conclusion Doctors should notice the rational compatibility proportion of Shengmai injection and 5% glucose injection in clinical use,

关 键 词：生脉注射液 5%葡萄糖注射液 不溶性微粒 

分 类 号：R969.2[医药卫生—药理学] R972[医药卫生—药学]