基于选择牵连效应的标记/性状关联分析方法简介  

Identification of important genes by marker-trait association analy- sis based on hitchhiking mapping

作　　者：游光霞[1] 张学勇[1] 

机构地区：[1]中国农业科学院作物科学研究所,农业部作物品种资源与生物技术重点实验室,北京100081

出　　处：《遗传》2007年第7期881-888,共8页Hereditas（Beijing)

基　　金：国家重点基础研究(编号:2004CB117202);国家高技术研究发展计划项目(国家863计划)(编号:20060110Z1136)资助项目~~

摘　　要：许多重要农艺性状如产量、品质、抗逆性等多表现为数量性状,是由多个基因和环境共同作用的结果,对其遗传基础的研究比较困难。近年发展起来的以选择牵连效应分析为基础,通过标记/性状之间的关联分析方法为这些性状的作图和遗传解析提供了新的手段,也为作物的分子设计育种提供了新的思路,其与QTL作图结果互相验证、互相补充,必将促进数量遗传学、应用基因组学和育种学的发展。文章对关联分析的思路、方法、优缺点及应用时应注意的问题进行了比较系统的介绍。Most agronomic traits such as yield, quality and stress-tolerance of crops are quantitative traits. It is not easy to dissect genetic basis of these traits because they are controlled by multi-genes that are affected by environmental factors. Hitchhiking mapping offers a new method for identifying of loci controlling those traits and assessing their allelic variations Marker-trait association analysis based on the hitchhiking effects will play an important role in dissection of complex traits. Combination of quantitative trait loci （QTL） mapping with marker-trait association analysis will facilitate dissection of complex traits, resulting in important information and markers for molecular breeding by design in crops. In this review, we presented a brief introduction of hitchhiking effects, marker-trait association analysis and practical considerations.

关 键 词：数量性状 连锁不平衡作图 选择牵连效应 关联分析 

分 类 号：S336[农业科学—作物遗传育种]