新城疫分离株与La Sota疫苗交叉免疫保护性研究  

A Cross Immunoprophylaxis Experiment with Chicken NDV Isolated Strain and NDV La Sota Vaccine Strain

作　　者：王爱华[1] 陈建新[2] 苏杰[1] 

机构地区：[1]河北北方学院动物科技学院医学系,河北张家口075000 [2]河北北方学院科研处,河北张家口075000

出　　处：《河北北方学院学报（自然科学版）》2007年第3期32-34,共3页Journal of Hebei North University:Natural Science Edition

基　　金：张家口市科技局资助项目(061151)

摘　　要：用新城疫(ND)分离强毒油佐剂灭活苗和NDV La Sota油佐剂灭活苗分别免疫带有新城疫母源抗体的雏鸡,免疫后每7d采集血清,用微量血凝抑制试验方法检测HI抗体.并于免疫后第21、28、35 d用鸡新城疫分离毒和NDV F_(48)E_9分别进行攻毒试验,结果显示,免疫鸡的HI抗体水平没有大的差异,分离毒株灭活苗对鸡新城疫强毒感染的免疫保护效力优于La Sota灭活苗.Chicken with NDV antibodiesis was immunized with the oil adjuvant inactivated vaccine NDV Isolated Strain and the oil adjuvant NDV LaSota strains vaccine. After the inoculability, the titres of the serum NDV antibodies were tested by the Micro-HI every 7 d. Immunized chickens were respectively challenged by NDV Isolated Strain and standard F48E9 in 21th, 28th and 35th day after immunization. The results showed that there was no difference between the two inactivated vaccine in immune efficacy. Isolated inactivated vaccine provided a better immune protection than La Sota inactivated Vaccine.

关 键 词：新城疫病毒 免疫保护 灭活苗 

分 类 号：S852.4[农业科学—基础兽医学]