急性一氧化碳中毒后迟发性脑病的临床与头颅磁共振改变  

Study of delayed encephalopathy after acute carbon monoxide poisoning by clinical characteristic and MRI features

作　　者：俱西驰[1] 王伟[2] 武成斌[1] 

机构地区：[1]西安交通大学第一附属医院神经内科,西安710061 [2]西安交通大学医学院,西安710061

出　　处：《中国实用神经疾病杂志》2007年第4期7-8,共2页Chinese Journal of Practical Nervous Diseases

摘　　要：目的探讨急性一氧化碳中毒后迟发性脑病(DEACMP)患者的头颅磁共振成像(MRI)特点和诊断价值。方法分析24例DEACMP患者的临床表现、头颅MRI资料。结果DEACMP患者的主要临床表现为智能、人格改变;头颅MRI表现为脑室周围白质和半卵圆中心双侧对称的点状、斑片状或融合性病灶,T2加权像呈高信号,T1加权像呈低信号,基底节或苍白球区呈慢性缺血性改变,偶见病灶主要位于大脑皮质。结论本病的诊断主要依靠病史、临床表现和头颅磁共振改变。Objective To explore the MRI features and MRI diagnosis value in delayed encephalopathy after acute carbon monoxide poising （DEACMP）. Methods The clinical and MRI data of 24 patients with DEACMP were analysed. Results The main clinical manifestation of the diseases were intellectual disturbances and personality disorders. The MRI showed that brain lesions in DEACMP were bilateral symmetric punctuate, spotty or confluent loci within periventricular white matter and centrum semioval, which showed high signal intensity in T2 - weighted and low signal intensity in T1- weighted . The chronic ischemia changes were found in the globus pallidus or basal ganglia areas. Cerebral cortex lesions were observed occasionally. Conclusion The diagnosis of DEACMP mainly depends on ease history,clinical features and MRI features.

关 键 词：急性一氧化碳中毒 迟发性脑病 磁共振成像 

分 类 号：R595.1[医药卫生—内科学]