抗辐射菌中DNA损伤修复主要基因群的研究进展  

Research Progress on Central Genes of DNA Repair in Radiation Resistant Deinococcus radiodurans

作　　者：施美星 屠振力[2] 

机构地区：[1]浙江环龙环境保护公司,浙江杭州310012 [2]浙江大学动物科学学院,浙江杭州310029

出　　处：《激光生物学报》2007年第3期374-378,F0003,共6页Acta Laser Biology Sinica

基　　金：教育部留学回国人员科研启动基金资助项目(J20040269);浙江省教育厅基金项目(G20040392);浙江省自然科学基金(Y305224);浙江省"钱江人才计划"项目(2006R10001)

摘　　要：抗辐射红色球菌对电离辐射具有很高的放射线抵抗性,该菌具有惊人的DNA的二条链切断的修复能力,由辐射等引起的切断损伤DNA在几至十几小时内能高效正确地进行完全修复。在对切断的双链DNA进行修复时,除了大肠杆菌等生物在切断的双链DNA修复时出现的蛋白质以外,还有该菌所特有的修复蛋白质也参与修复。本文对该菌所特有的DNA二条链的切断损伤修复的主要基因及其相互作用进行了简要介绍。Radiation resistant Deinococcus radiodurans has high radioresistance to ionizing radiation and astonished DNA strand break damage repair ability. DNA strand break damage caused by irradiation can be repaired correctly and effectively in a certain time. Duing DNA strand break repairs, the same damage repair protein that appeared in E. coli DNA damage repairs appeared, and peculiar repair protein of Deinococcus radiodurans also participate in the repairs. In this paper, these central repair genes and their interaction were concisely introduced.

关 键 词：抗辐射菌 辐射抗性 DNA损伤修复 基因群 

分 类 号：Q937[生物学—微生物学] R811.5[医药卫生—放射医学]