芬布芬电化学行为的线性扫描极谱法研究  

Study on Fenbufen Electrochemical Behavior by the Linear Scanning Polarographic Method

作　　者：谢天阳[1] 拓宏桂[1] 丁马太[1] 

机构地区：[1]龙岩学院化学与材料工程系,福建龙岩364000

出　　处：《电化学》2007年第2期212-215,共4页Journal of Electrochemistry

基　　金：褔建省教育厅自然科学基金项目(JA03165)资助

摘　　要：应用线性扫描极谱法研究芬布芬的电化学行为.在0.2mol.L-1Na2HPO4-KH2PO4缓冲溶液(pH6.86)中,芬布芬于-1.38V(vs.SCE)处产生一灵敏的吸附波,其一次微分线性扫描峰电流与芬布芬浓度呈良好的线性关系,浓度范围1.6～200.0mg.L-1,相关系数r=0.9958(n=10),检出限为0.8mg.L-1.以80.0mg.L-1芬布芬溶液作6次平行试验,RSD为0.73%,回收率在97.7%～109.2%之间.芬布芬的此一电化学特性可用于其片剂含量测定.The electrochemical behavior of fenbufen had been studied by linear scanning polarographic method. In 0.2mol L^-1 phosphate buffer solution （pH6.86）, a sensitive reductive wave of fenbufen appeared at - 1.38 V （ vs. SCE）. The linear relationship between the peak current and the fenbufen concentration in the range of 1.6 -200.0 mg .L^-1 （r = 0. 9958 ,n = 10） were observed, the detection limit of this method was 0.8 mg.L^-1. RSD is 0.73%, found from the data of 6 independent determinations at the concentration level of 80.0 mg . L^-1. recovery ratio is 97.7% -109.2% . This fenbufens electrochemical characteristic property may be used to determining the contents of tablets.

关 键 词：药物分析 芬布芬 线性扫描极谱法 吸附波 

分 类 号：O646.5[理学—物理化学]