金电极上放线菌素D的电化学行为及分析测定  

Square Wave Stripping Voltammetric Behaviors of Actinomycin D on Glod Electrode and Its Application

作　　者：朱清涛[1] 廖钫[1] 何晓英[1] 

机构地区：[1]西华师范大学化学化工学院,四川南充637002

出　　处：《电化学》2007年第2期216-219,共4页Journal of Electrochemistry

基　　金：四川省教育厅重点研究课题(2004A106);西华师范大学校级重点项目(06A009)资助

摘　　要：应用方波溶出伏安法研究了放线菌素D在KH2PO4-Na2HPO4缓冲溶液中于金电极上的电化学行为以及酸度、预富集沉积电位、预富集沉积时间、方波频率、方波幅度、电位增量等的影响,优化测定参数,建立一种直接测定放线菌素D的电分析测定方法.在0.1～10.0μmol.L-1浓度范围内,放线菌素D与其方波溶出伏安氧化峰电流呈良好的线性关系,相关系数0.9991,检测限1.0×10-8mol.L-1.The electrochemical behaviors of Actinomycin D （ACTD） at glod electrode were investigated by square wave stripping voltammeter in the KH2PO4-Na2 HPO4 buffer solution （pH = 5.90）. The sensitive oxidation peak of ACTD was observed and the potential peak for ACTD is - 0.17 V （ vs. SCE）. The Experimental parameters, such as pH value, amplitude, accumulation potential and time were optimized, and a direct electroanalytical method for determining ACTD was developed. The peak currents were proportional to the concentration of ACTD in the range of 0. 1μmol. L^-1 - 10.0μmol . L^-1, and the linear regression coefficient equaled 0. 9991. The detection limit for ACTD was 1.0 × 10^-8mol . L^-1.

关 键 词：放线菌素D 方波浴出伏安法 金电极 电化学检测 

分 类 号：O646.54[理学—物理化学]