补虚散结胶囊对小鼠Lewis肺癌细胞增殖动力学的影响  

Effect of Buxu Sanjie Capsule on Multiplication Dynamics of Lewis Cells of Mice with Lung Cancer

作　　者：后盾[1] 刘望姣[1] 高允珊[1] 李宏良[2] 邱侠[1] 杨怀新[1] 杨振江[1] 

机构地区：[1]广东省深圳市中医院,深圳518001 [2]广州中医药大学

出　　处：《河北中医药学报》2007年第2期10-11,共2页Journal of Hebei Traditional Chinese Medicine and Pharmacology

摘　　要：目的:观察补虚散结胶囊对肺癌瘤株Lewis肺癌细胞增殖动力学的影响,探讨补虚散结胶囊治疗肺癌疗效机理。方法:用血清药理学方法进行增效试验,MTT法检测A590值,以每组测得光密度平均值作为药物效应值。结果:补虚散结胶囊配合替加氟组Lewis肺癌细胞存活率低于单纯替加氟组。结论:补虚散结胶囊配合化疗疗效满意,其疗效机理与补虚散结胶囊抑制肿瘤细胞增殖有关。Objective: to observe theeffect of Buxu Sanjie Capsule on multiplication dynamics of Lewis cells of mice with lung cancer, and to discuss its curative mechanismin treating lung cancer. Methods: Serum pharmacologywas used to conduct synergia experiment, MTT to examine A590 withthe average optical density as drug effector. Results: survival rate of Lewis cells in Buxu Sanjie Capsuleand Tegafur group was lower than that in pure Tegafur group. Conclusion:Buxu Sanjie Capsule in addition to chemotherapyhas better curative effect, whose mechanism may be relevant to its inhibiting multiplication of tumor cells.

关 键 词：补虚散结胶囊 小鼠Lewis肺癌瘤株 增殖动力学 

分 类 号：R273[医药卫生—中西医结合]