铑催化不对称1,4-共轭加成反应的研究进展  

Progress in Rhodium-Catalyzed Asymmetric 1,4-Conjugate Addition Reactions

作　　者：王欢[1] 杨定乔[1] 莫海洪[1] 

机构地区：[1]华南师范大学化学与环境学院,广州510006

出　　处：《有机化学》2007年第7期806-818,共13页Chinese Journal of Organic Chemistry

基　　金：广东省自然科学基金(No.04010404)资助项目.

摘　　要：铑催化不对称1,4-共轭加成反应是一种非常有效的碳—碳键形成方法.综述了近年来铑催化不对称1,4-共轭加成反应的研究进展,包括α,β-不饱和酮、酯、酰胺、醛和砜等与某些亲核试剂的1,4-共轭加成反应.Rhodium-catalyzed asymmetric 1,4-conjugate addition reaction is one of the most efficient methods for the carbon-carbon bond formation. In this paper, the recent progress in rhodium-catalyzed asymmetric 1,4-conjugate addition reactions is reviewed. Asymmetric 1,4-conjugate additions of α,β-unsaturated ketones, esters, amides, aldehydes, sulfones and so on with some nucleophiles are presented.

关 键 词：铑催化 不对称 亲核试剂 1 4-共轭加成 

分 类 号：O643.32[理学—物理化学]