心肌缺血／再灌注损伤的基因治疗  

Gene therapy for myocardial ischemia and reperfusion injury

作　　者：姜金玉[1] 杨昭云[1] 徐军美 

机构地区：[1]中南大学湘雅二医院麻醉科,长沙410011

出　　处：《国际麻醉学与复苏杂志》2007年第3期231-234,共4页International Journal of Anesthesiology and Resuscitation

摘　　要：缺血/再灌注损伤是多种心肌疾病重要的病理生理环节,目前主要的治疗措施有缺血预处理及多种药物的预处理,也都显示出了一定的保护效应。近年来应用基因治疗的方法为缺血/再灌注损伤的治疗提供了全新和有效的途径,现就此方面的研究进展作一简介。Ischemia and reperfusion （I/R） injury is a vital pathological element for various heart diseases. Current therapy including I/R preconditioning and pharmacological preconditioning has shown some protective effects for these heart diseases, Gene therapy provides a novel effective approach for I/R injury in recent years. This review focuses on the advance in gene therapy for myocardial ischemia and reperfusion injury.

关 键 词：缺血/再灌注损伤 心脏 基因治疗 

分 类 号：R4[医药卫生—临床医学] R54