职业紧张对火车司机血清白细胞介素-6水平的影响  

EFFECT OF OCCUPATIONAL STRESS ON SERUM INTERLEUKIN-6 LEVEL OF LOCOMOTIVE ENGINEER

作　　者：任领华 曹煜红[1] 仇丽霞[2] 郭玮[1] 赵芳[1] 高征[1] 

机构地区：[1]山西太原铁路局疾病预防控制中心,太原030013 [2]山西医科大学公共卫生学院

出　　处：《现代预防医学》2007年第13期2477-2478,共2页Modern Preventive Medicine

摘　　要：[目的]探讨职业紧张对火车司机血清中白细胞介素-6水平的影响。[方法]采用随机抽样方法抽取某铁路局的火车司机208人为调查对象,使用职业紧张因素量表(OSI)中的职业紧张来源部分对其职业紧张状况进行调查,采用放射免疫法分析血清中IL-6浓度。[结果]火车司机血清中IL-6的浓度为(125.17±49.81)pg/ml,95%的可信限为119.15～131.18pg/ml。以血清中的IL-6浓度为应变量进行逐步回归分析(α入=0.10,α出=0.15),来源于人际关系、职务特征的职业紧张因素进入了回归方程。方差分析结果显示,来源于人际关系和职务特征的职业紧张因素评分组间血清IL-6浓度差异无统计学意义(P﹥0.05)。火车司机血清中的IL-6浓度与年龄、婚姻状况、文化程度等因素无关。[结论]职业紧张对火车司机血清中IL-6浓度的升高有一定影响。[ Objective] To explore the effects of occupational stress on interleukin-6 level of locomotive engineers. [ Methods]208 locomotive engineers in railway station were investigated for occupational stress status by questionnaires （OS-Ⅰ） . Serum interleukin-6 concentration was measured by radio-immune-assay. [ Flesults] Serum interleukin-6 concentration of locomotive engineers was （125.17 4± 49.81） pg/ml with 95% confidence interval （CI） of 119.15-131.18 pg/ml. Stepwise regression analysis （αin= 0.10,αout= 0.15） showed that occupational stressors from social relation and professional features were the significant predictors of serum 1L-6 level. ANOVA revealed that the level of IL-6 in the serum of the subjects with higher scores of occupational stressors was not higher （P〉 0.05） . Serum IL-6 level of locomotive engineers didn＇t relate to age, marital status and education. [Conclusion] Occupational stress may result in the increase of serum IL-6 level of locomotive engineers.

关 键 词：职业紧张 火车司机 白细胞介素-6 血清 

分 类 号：R135.99[医药卫生—劳动卫生]