鼻咽癌放疗后分泌性中耳炎的治疗  

Treatment for secretory otitis media in nasopharyngeal carcinoma patients after radiotherapy

作　　者：游舟[1] 杨柏球 刘理[1] 

机构地区：[1]湖南省岳阳市第二人民医院耳鼻咽喉科,湖南岳阳414000

出　　处：《中国耳鼻咽喉颅底外科杂志》2007年第3期218-220,共3页Chinese Journal of Otorhinolaryngology-skull Base Surgery

摘　　要：目的探讨治疗鼻咽癌放疗后分泌性中耳炎的治疗方法。方法将60例鼻咽癌放疗后并发分泌性中耳炎患者随机分为A、B两组,每组30例。A组鼓室置管;B组在鼻内镜下行鼻腔鼻咽部清理加鼓膜穿刺抽液加鼓室给药沐舒坦。比较分析两组治疗效果及并发症。结果随访10个月,60例中存活49例。存活患者中,分泌性中耳炎治疗有效率A组为52.6%,B组为81.6%,差异有统计学意义(P<0.05);并发症发生率A组为23.7%,B组为7.9%,差异有统计学意义(P<0.05)。结论对鼻咽癌放疗后伴发的分泌性中耳炎治疗,鼻腔鼻咽部清理加鼓膜穿刺抽液加鼓室给药沐舒坦优于单纯鼓室置管引流。Objective To discuss the clinical treatment for secretory otitis media （SOM） in nasopharyngeal carcinoma （NPC） patients after radiotherapy. Methods 60 NPC patients with SOM after radiotherapy were randomly divided into two groups： patients in group A received tube insertion for ventilation and patients in group B were treated with nasal and nasopharyngeal debridement, tympanic membrane puncture and suction combined with tympanic injection of ambroxol solution. The therapeutic effect and complications between the two groups were compared after patients were followed up for ten months. Results After 10 months follow-up, 49 patients survived with effective rates of 52. 6% and 81.6N and with complication rates of 23. 7%, and 7. 9% in group A and B respectively, the differences of effective rates and complication rates between the two groups were both statistically significant （ P 〈0. 05）. Conehtsion For SOM in NPC patients after radiotherapy, the effect of combined therapy of nasal and nasopharyngeal debridement, tympanic membrane puncture and suction, as well as tympanic injection of ambroxol solution is superior to that of tube insertion.

关 键 词：鼻咽肿瘤 中耳炎 治疗 

分 类 号：R764.21[医药卫生—耳鼻咽喉科]