细胞凋亡检测方法研究进展  

Progress on research method of cell apoptosis

作　　者：吕莹[1] 张德禄[2] 张宏[1] 王高鸿[2] 刘永定[2] 胡春香[2] 

机构地区：[1]西北师范大学生命科学学院,甘肃兰州730070 [2]中国科学院水生生物研究所,湖北武汉430072

出　　处：《西北师范大学学报（自然科学版）》2007年第2期82-87,共6页Journal of Northwest Normal University(Natural Science)

基　　金：国家自然科学基金资助项目(30170112);中国科学院知识创新工程资助项目(KSCX2-SW-322);国家载人航天工程资助项目

摘　　要：细胞凋亡是生命科学目前的一个研究热点.检测细胞凋亡的方法和技术取得了很大的进步.从早期细胞内某些基因转录表达的变化、代谢生理的变化,到晚期细胞形态的确诊、细胞内代谢物质的转变,从定性、定量到原位定性定量等,都发展了相对成熟的检测技术.根据检测时间的早晚,从形态学、生化特性和分子调控等层次综合分析了检测细胞凋亡的主要方法,并对相关研究进行了展望.The study of research focuses of life developed. Now many cell apoptosis has obtained mu science, and the relat methods can assay ear ive assay ly change ch more development in present days as one of methods have also been obviously improved and on cell apoptosis from genetic transcription and expression level and metabolic and both in nature and ration morphology, biochemistry and realm in the future are made a physiology level to of apoptotic cell in molecular biology prospect as well. late variation in situ have been is reviwed minu cell morphologic structure, metabolite, invented. The research development in tely, and the relative researches of this

关 键 词：细胞凋亡 检测方法 细胞坏死 

分 类 号：Q26[生物学—细胞生物学]