结核性脑膜炎脑脊液中粒细胞集落刺激因子的测定  

Measurement of Granlocytes Colony-Stimulating Factor (G-CSF) in Cerebrospinal Fluid (CSF) from patients with Tuberculous Meningitis

作　　者：王北宁[1] 韩玲霞[1] 靳淑玲[1] 李彩[1] 王宁宁[2] 

机构地区：[1]北京军区总医院,100700 [2]长春208医院

出　　处：《中国防痨杂志》1997年第1期29-30,共2页Chinese Journal of Antituberculosis

摘　　要：本文采用ＥＬＩＳＡ法检测２３例结核性脑膜炎及２１例非结核性脑膜炎脑脊液中的Ｇ－ＣＳＦ。结脑组（０．６５＋０．３２ＯＤ）明显高于非结脑组（０．１５±０．１１ＯＤ）（Ｐ＜０．０１）。诊断结脑的敏感性为９１．３％，特异性为９０．５％。Ｇ－ＣＳＦ在抗感染的非特异性细胞免疫中起重要作用，细菌及其产物是刺激和调节Ｇ－ＣＳＦ产生的主要物质。G-CSF was measured in 23 cases of tuherculous meningitis and 21 cases of nontuberculous meningitis using ELISA method. The G-CSF levels of CSF in group of tuherculuus meningitis (0. 65±0. 32OD) were significantly higher than group of nontu- berculous meningitis (0. 15±0.11OD) (P<0. 01). Their positive rates were shown to be 91. 3% and 90. 5% respectively. The differ- ence between the two groups was statistically singnificant ( P<0. 01). The sensitiviity, specificity and accuracy were 91. 3%, 90. 5% and 90. 9% respectively for diagnosis of tuberculous meningitis.

关 键 词：结核性脑膜炎 脑脊液 G-CSF 测定 

分 类 号：R529.3[医药卫生—内科学]