快速ELISA检测血清抗PPD-IgG对肺结核的诊断价值  

Detection of Anti-PPD-IgG in serum for the Diagnosis of Pulmonary Tuberculosis by Rapid ELISA

作　　者：秦光祖 汪月华 范四禄 吴洛琳 

机构地区：[1]桂林市第三人民医院,541002

出　　处：《中国防痨杂志》1997年第1期31-32,共2页Chinese Journal of Antituberculosis

摘　　要：目的评价抗PPD－IgG检测对活动性肺结核的诊断价值。方法采用快速酶联免疫吸附法(ELISA)检测340例活动性肺结核、56例非活动性肺结核、88例非结核性病人血清中的抗PPD－IgG。结果活动性肺结核组抗PPD－IgG阳性率为83．8％,其中痰涂片(＋)组为92．2％,涂片(－)组为78．7％。非活动性肺结核组3例阳性,非结核组5例阳性,假阳性率分别为7．1％和5．7％。本法敏感性为83．8％,特异性为93．8％,准确性为86．8％,阳性预测值为96．9％,阴性预测值71．1％。结论。提示血清抗PPD－IgG测定是肺结核病人一项有用的辅助诊断手段。Objection To ascertain the value of anti-PPD-IgG detction in the diagnosis of pulmonary tuberculosis. Methods Anti-PPD-IgG in serums were obtained from 340 cases with active pulmonary tuberculosis, 56 cases with nonactive pulmonary tuberculosis and 88 cases without tuberculosis were detected by using rapid enzyme-linked immunosor-bent assay (ELISA). Results The positive rate of anti-PPD-IgG was 83. 8% in active pulmonary tuberculosis group, and the flase posi- tive rate were 7. 1% and 5. 7% in nonactive pulmonary tuberculosis group and without tuberculosis patients respectively. It was demonstrated that the sensitivity, specificity and accuracy of this method to diagnosis tuberculosis were 83. 8%, 93.% and 86. 3%,the positive and negative predictivities of this method were 96. 9% and 71.1%. Conclusion The results suggest-ed that rapid ELISA for anti-PPD-IgG detection is a useful auxiliary tool for diagnosis of pulmonary tuber-culosis.

关 键 词：肺结核 诊断 ELISA PPD-IGG 

分 类 号：R521.04[医药卫生—内科学]