苦碟子注射液致过敏反应  

Allergy caused by Kudiezi injection

作　　者：谭文超[1] 苑冬敏[1] 

机构地区：[1]辽宁中医药大学附属医院药剂科,沈阳110032

出　　处：《药物不良反应杂志》2007年第3期219-219,213,共2页Adverse Drug Reactions Journal

摘　　要：77岁女性冠心病(不稳定型心绞痛)患者,静脉滴注苦碟子注射液40ml,1次/d。治疗第3天静脉滴药液10min时,出现周身发抖,四肢冰冷,心悸,恶心,呕吐。查体:T37.3℃,P95次/min,BP150/100mmHg。立即停药,给予对症治疗。0.5h后,患者又出现恶心、呕吐,T39.4℃,P84次/min,BP140/80mmHg,给予溴米那普鲁卡因2ml肌内注射和对症治疗,4h后患者T37.9℃,P75次/min,BP95/60mmHg,自觉症状明显缓解。A 77-year-old woman with coronary heart disease and unstable angina was administered with Kudiezi injection 40ml once daily. On day 3, after ten minutes of infusion, she developed shudder, cold limbs, palpitation, nausea, and vomiting. A physical examination showed the following values： T 37.3℃, P 95 times/min, BP 150/100 mmHg. Immediately, Kudiezi injection was withdrawn and she was given symptomatic therapy. A half hour later, the patient occurred nausea and vomiting again. A re-examination revealed the values as follows： T 39.4℃, P 84 times/min, BPI40/80 mmHg. Four hours after administration ofIM bromisoval procaine 2 ml and symptomatic therapy, she recovered with a body temperature of 37.9℃, a pulse of 75 times/min, a BP of 95/60 mmHg. She felt the symptoms relieved obviously.

关 键 词：苦碟子注射液 过敏反应 

分 类 号：R595.3[医药卫生—内科学]