动脉血碱缺失指标变化在脓毒症液体复苏早期的临床意义  

Significance of Arterial Base Deficit in Patients with Sepsis Resuscitation

作　　者：杨孟选[1] 刘保池[1] 可妮 李光源 陈秀春 李琮宇[3] 

机构地区：[1]郑州大学第一附属医院急救中心 [2]郑州大学医学实验中心癌症研究室,郑州450052 [3]河南省食管癌重点开放实验室,平顶山第四人民医院平顶山467003

出　　处：《河南职工医学院学报》2007年第1期4-6,共3页Journal of Henan Medical College For Staff and Workers

摘　　要：目的分析脓毒症早期动脉血BD值的变化规律以及脓毒症患者液体复苏时BD的临床意义。方法回顾分析56例脓毒症患者液体复苏时,BD值的动态变化,比较存活组和死亡组BD值的变化及BD与患者预后之间的关系。结果脓毒症早期BD逐渐升高,存活组患病后4-8 h期间BD显著提高(P<0.05),死亡组与存活组差异显著(P<0.05)。死亡组的多器官衰竭发生率亦明显高于存活组(P<0.05)。结论BD值可作为脓毒症早期液体复苏时的监测指标之一,4-24 h期间BD值仍持续低水平可能提示预后不良。Objective To investigate the changes of arterial Base Deficits （BD） in sepsis patients and analyze clinical significance of arterial base deficit in patients with sepsis resuscitation. Methods By performing a retro-spectivereview of 56 cases of sepsis, whose data of BD changes were observed for 48-hours real-time monitoring, contrasting the BD data of the survivor group and death group and analyzing the relationship of BD and prognosis in the two groups. Results The dada of BD was increasing gradually in the patients of early stage of sepsis, which was significantly higher in survivor group than that of death group between 4 hours and 8 hours after developing sepsis （P 〈 0.05）. There was statistical difference between survivor group and death group（ P 〈 0.05 ）. The arising of organs failure rate of death group was significantly higher than that of survivor group（P 〈 0.05）. Conclusion BD can be one of the chief monitoring marks when the fluid resuscitation adopt in the early stage after sepsis developing. Currently, the method of fluid resuscitation is still one of the efficient methods of improving low perfusion state. During the cure process if the BD is still in lower level in the early stage of sepsis maybe indicate worse prognosis.

关 键 词：脓毒症 多器官功能衰竭 复苏 碱缺失 

分 类 号：R631.2[医药卫生—外科学]