Ⅱ型糖尿病患者的红细胞免疫功能  

Red Blood Cell Immune Function in Patients with Type Ⅱ Diabetes

作　　者：吴艺捷[1,2] 刘若英[1,2] 张家秀[1,2] 谭生荣[1,2] 徐淑静[1,2] 费樱[1,2] 

机构地区：[1]贵阳医学院附院内分泌科 [2]贵阳医学院附院免疫科

出　　处：《贵阳医学院学报》1997年第1期33-35,共3页Journal of Guiyang Medical College

基　　金：贵州省科委基金

摘　　要：观察５１例Ⅱ型糖尿病患者的红细胞Ｃ３ｂ受体花环率（ＲＢＣ－Ｃ３ｂＲＲ），红细胞免疫复合物花环率（ＲＢＣ－ＩＣＲ）和循环免疫复合物（ＣＩＣ）。结果与对照组相比，糖尿病患者ＲＢＣ－Ｃ３ｂＲＲ明显降低，ＲＢＣ－ＩＣＲ明显升高，ＣＩＣ阳性率亦增加，这些变化随着糖尿病患者病程延长而更为突出。本文结果提示Ⅱ型糖尿病患者存在红细胞免疫粘附功能的降低，这种变化可能是糖尿病病程中出现的一种继发性改变。In this study red blood cell C 3b receptor rate (RBC C 3bRR),red blood cell immune complex rate (RBC ICR) and circulating immune complex (CIC) were determined in 51 patients with type Ⅱ diabetes The results showed that the RBC C 3bRR was significantly decreased and the RBC ICR as well as the CIC positive rate were remarkably increased in the diabetic patients as compared with the control The RBC C 3bRR, RBC ICR and CIC positive rate in type Ⅱ diabetes were 16 71±7 31, 5 87±3 18 and 27 6% but in controls were 22 38±7 60,3 64±2 97 and 6 2%, respectively The changes became more remarkable when the patients had longer diabetic processes The RBC C 3bRR in Group A,B and C of diabetes was 20 12±5 97,17 01±7 11 and 15 43±6 76,respectively and the RBC ICR was 4 32±2 77,5 61±2 91 and 7 04±3 01,respectively Our results suggest that there is decrease of the red blood cell immune adherence function in the diabetic patients This may be one of the causes for secondary change in the diabetic process

关 键 词：糖尿病 红细胞 免疫复合物 

分 类 号：R587.103[医药卫生—内分泌]