用化学发光法检测芦丁等物质清除超氧阴离子自由基的作用  

The scavenging effect of rutin etc.on superoxide radicals with chemiluminescent method

作　　者：郑学钦[1,2] 胡春 

机构地区：[1]福建中医学院附属人民医院 [2]广州大学轻工系

出　　处：《中国药学杂志》1997年第3期140-142,共3页Chinese Pharmaceutical Journal

摘　　要：目的：考察茶叶、野菊花、山楂、芦丁对超氧阴离子自由基的清除作用。方法：以黄嘌呤黄嘌呤氧化酶鲁米诺体系作为超氧阴离子的产生体系，以化学发光的降低作为检测活力的指标。结果：茶叶、野菊花、山楂、芦丁都表现出对超氧阴离子自由基的清除作用，其活力与黄酮含量有关。结论：黄酮类化合物对超氧阴离子自由基的清除是有效的。OBJECTIVE:To determine the scavenging effect of tea,Chrysanthemum indicum L.,hawthorn and rutin on superoxide radicals.METHODS:Reduction of chemiluminescence worked as an index of activity with xanthine xanthine oxidase luminol system as superoxide radicals generating system.RESULTS:Tea,Chrysanthemum idicum L.,hawthorn and rutin showed scavenging effect on superoxide radicals.The activity was related to its flavonoid content.CONCLUSION:Flavonoid was effective in scavenging superoxide radicals.

关 键 词：化学发光 超氧阴离子 自由基 黄桐 芦丁 

分 类 号：R284.1[医药卫生—中药学]