原发性痛风家系男性与女性痛风病人的比较  

COMPARISON OF MALE AND FEMALE GOUT PATIENTS FROM GOUT AND HYPERURICEMIA FAMILY

作　　者：纪艳[1] 吴秀英[1] 李长贵[1] 苗志敏[1] 闫胜利[1] 王颜刚[1] 

机构地区：[1]青岛大学医学院附属医院内分泌科,山东青岛266003

出　　处：《青岛大学医学院学报》2007年第4期357-358,共2页Acta Academiae Medicinae Qingdao Universitatis

基　　金：国家自然科学基金;青岛市科技局重大项目资助(30470821;30570890;N3-1-NY-14-1)

摘　　要：目的探讨原发性痛风家系不同性别病人的临床特点。方法对比分析19个原发性痛风家系中40例男性病人和19例女性病人的临床特征及生化检测指标。结果女性36～45岁年龄段痛风构成比明显低于男性(χ2=6.01,P<0.05)。并发肥胖、高血压、糖代谢紊乱、脂代谢紊乱的概率女性病人与男性病人相比差异无统计学意义。女性痛风病人腰臀比、TG明显低于男性痛风病人(t=3.29、3.81,P<0.01),BUN明显高于男性痛风病人(t=3.00,P<0.05)。结论对于有痛风家族史的病人(无论男性还是女性),应定期查体,以便早期发现和及时治疗痛风。Objective To study the clinical characteristics of male and female gout patients from gout family. Methods To compare and analyze the clinical characteristics and laboratory data of 40 male and 19 female patients from 19 gout families. Results The constituent ratio of female patients at the age of 36-45 years was lower compared with the male patients （X^2=6.01, P〈0.05）. The levels of TG and WHRin the female patients were significantly lower than those in the male （t=3.29,3.81;P〈 0.05）. BUN level in the female patients was significantly higher than in the male （t- 3.00, P〈0.05）. Conclusion Regular medical examination is recommended to family members with a familial history of gout in order to get early diagnosis and treatment for new patients.

关 键 词：原发性痛风 高尿酸血症 家系 

分 类 号：R589.7[医药卫生—内分泌]