重度子痫前期孕妇器官受累情况与新生儿预后的关系  

Relations between the lying in woman with severe preeclampsia involving damage of organs and neonatal prognosis

作　　者：肖成炜[1] 

机构地区：[1]蚌埠医学院第二附属医院妇产科,安徽蚌埠233040

出　　处：《蚌埠医学院学报》2007年第4期410-412,共3页Journal of Bengbu Medical College

摘　　要：目的:探讨重度子痫前期器官受累特点,分析早发型和晚发型重度子痫前期各种器官受累情况与新生儿预后的关系。方法:回顾性分析80例重度子痫前期患者及其新生儿临床资料。将重度子痫前期起病时间以34孕周为界分为早发型和晚发型两组;比较两组一般情况、器官受累情况、并发症或合并症及母婴结局。结果:早发型重度子痫器官损害以胎盘为主,胎盘损害发生率比晚发型有显著升高(P<0.005);伴有器官受累者的新生儿预后较无受累者差;在伴有器官受累者中,早发型新生儿预后较晚发型差。结论:重度子痫前期发病时间越早、器官受累越严重,其围生儿预后不佳,应根据母婴情况积极治疗。同时密切监测母胎病情变化,适时终止妊娠。Objective：To analyze the characteristics of early and late onset severe preeclampsia（S-PE） involving organ damage and its relations with neonatal prognosis. Methods：Eighty mothers with severe preeclampsia and their 80 neonates were divived to two groups according to the onset time of severe preeclampsia： onset ≤34 weeks group and 〉 34 weeks group. The clinical data,pattern of organ damage, complications, and maternal and neonatal outcomes were analyzed. Results ： Placenta was the main organ damaged in the early onset group, and the occurrence rate was higher than that in the late onset group （P 〈 0. 005 ）. Perinatal mortality was much higher in patients with organ damage than in those without organ damage. The early onset group had a poorer outcome than the late onset group. Conclusions：The earlier the onset of S-PE occurred,the severer the pathogenetic condtion is, and poorer the perinatal outcomes will he. Proper treatment and monitoring is essential for mothers with S-PE and the foetus. Pregnancy should be terminated in some of the cases if nessessary.

关 键 词：子痫前期 胎盘损害 围产期学 婴儿 新生 疾病 

分 类 号：R714.244[医药卫生—妇产科学]