植物胞外多肽与人细胞因子的结构特征比较  

The Comparison of the Structure Between Extracellular Polypeptide of Plant and Human Cytokines

作　　者：柳辉[1] 郭毅[1] 

机构地区：[1]河北师范大学生命科学学院

出　　处：《河北师范大学学报（自然科学版）》2007年第4期527-530,534,共5页Journal of Hebei Normal University：Natural Science

基　　金：国家自然科学基金(30600043);河北省自然科学基金(C2006000142);河北师范大学科研基金(L2004Y06);河北师范大学博士基金(L2005B24)

摘　　要：植物细胞外多肽信使已经被证实是植物信号转导中重要的第一信使,运用生物信息学的方法,分析比较了已知的植物胞外多肽和人的细胞因子的氨基酸序列,发现这些来自不同界别的胞外多肽具有某些共同的结构特征,利用在线工具对胞外多肽的结构特征进行了验证,并根据细胞外多肽的结构特征推测了钙调素受体的三维结构,这些结果对发现新的植物胞外多肽及推测其可能的受体有重要意义.Extracellular polypeptides of plant have been proved to be important signals in signal transduction. Using tools of bioinformatics, the amino acid sequence of these extracellular polypeptides of plant, animal and microbe were studied. Some interesting results were found that there is some common character about extracellular polypeptide from different species, which is the very correlative 3D structure. Using bioinformatics tool, the 3D structure of receptor of calmodulin,an important new extracellular polypeptides of plant was given. What were found would help to identify new extracellular polypeptides of plant.

关 键 词：胞外多肽 细胞因子 结构 生物信息学 

分 类 号：Q291[生物学—细胞生物学]