静脉多巴胺用药浓度对新生儿局部皮肤不良反应的影响  

The adverse effects of different fluid concentration of dopamine on newborns＇ skin when who have accepted vein transfusion

作　　者：郑春华[1] 赵灵芳[1] 陈丽丽[1] 杨君平[1] 

机构地区：[1]浙江省台州医院新生儿科,临海317000

出　　处：《中国实用护理杂志》2007年第3期32-33,共2页Chinese Journal of Practical Nursing

摘　　要：目的 研究新生儿静脉应用多巴胺时不同的药物浓度对局部皮肤不良反应的影响，为新生儿临床应用该药的防护提供依据。方法 将157例入住重症监护病房的新生儿，按照所属医疗组分为A组57例，B组50例和C组50例。分别以0．1‰（A组）、0．075％。（B组）和0．05％0（C组）的浓度静脉输入多巴胺，观察3组局部不良反应的发生情况。结果 A组57例，严重不良反应11例占19．3％，轻度不良反应44例占77．2％；B组50例，严重不良反应2例占4．0％，轻度不良反应为29例占58．0％；C组50例，严重不良反应0例，轻度不良反应10例占20．0％。无论严重或轻度不良反应，A组显著多于B、C组（P〈0．05）；B组轻度不良反应显著多于C组（P〈0．05）；C组未出现严重不良反应。结论新生儿静脉输注多巴胺浓度在0．05‰时，使用较安全。Objective To study the adverse effects of different fluid concentration of dopamine on newborns＇skin when who have accepted vein transfusion, and then provide proper suggestion for clinical application. Methods Divided 157 newborns who had lived in the intensive care unit into A group （57 cases）, B group （50 cases） and C group （50 cases） according to their clinical adscription. 0.1‰ dopamine, 0.075‰ dopamine and 0.05‰ dopamine were used in these 3 groups respectively, and then observed the adverse effects of newborns＇skin for them. Results The incidence rate of serious adverse effects of newborns＇skin in the A, B and C group was 19.3%, 4.0% and 0 respectively. In general, the incidence rate of adverse effects in A group was significant higher than that of in B and C group,P〈O.05, and the incidence rate of adverse effects in B group was significant higher than that of in C group,P〈0.05. Condusious 0.05‰ dopamine for vein transfusion is proper for newborns who have in the intensive care unit, which can guarantee the safety for them.

关 键 词：新生儿 多巴胺 浓度 不良反应 

分 类 号：R7[医药卫生—临床医学]