献血感染人类免疫缺陷病毒/获得性免疫缺陷综合征患者201例:应对策略及生活质量调查  

201 HIV/AIDS subjects infected by plasma donation:An investigation on coping strategy and quality of life

作　　者：宁南义 石川[2] 于欣[2] 陈玉芳[2] 吴尊友[3] Ofilio Vigil Lucette A.Cysique Donald R.Franklin Jr Robert K.Heaton Igor Grant 

机构地区：[1]阜阳市第三人民医院,安徽省阜阳市236015 [2]北京大学精神卫生研究所,北京市100083 [3]中国疾病控制中心,北京市100050 [4]加州大学圣地亚哥分校HIV神经行为研究中心,美国圣地亚哥92103

出　　处：《中国组织工程研究与临床康复》2007年第28期5503-5506,共4页Journal of Clinical Rehabilitative Tissue Engineering Research

基　　金：NIMH资助(RO1MH073433-01A1)~~

摘　　要：目的:调查通过献血途径感染人类免疫缺陷病毒患者的应对方式及生活质量。方法:本调查于2006-01/07完成。共选取201例通过献血途径感染人类免疫缺陷病毒者入病例组,其中113例诊断为获得性免疫缺陷综合征。另取200例年龄、性别和受教育年限匹配的人类免疫缺陷病毒阴性献血者作为对照组。调查对象均签署知情同意书。采用Carver应付策略问卷简版和SF-36生存质量问卷进行调查:①Carver应付策略问卷简版:包括14个分量表,每个分量表包括两个条目,采用4级评分,1代表从来没这么做,4代表常常这样做,每个分量表粗分总分为8。②SF-36生存质量问卷:包括8个维度,各维度采用转换分数记分,最高分100分,最低分0分。生理健康总分和心理健康总分按标准分计算。分析Carver应对策略问卷的验证性因素及信度,比较两组调查对象的应对策略及生活质量,对人类免疫缺陷病毒感染者的应对方式与生活质量进行相关性分析。结果:发出问卷430份,选出内容详实问卷401份,有效率为93.3%。①Carver应付策略问卷中文版各因子的Cronbach’sα系数在0.55～0.84之间,14个因子模型验证性因素分析各拟合指标分别为χ2/df=0.49,IFI=1.05,AGFI=0.93,CFI=1.00,NNFI=1.07,MI=0.44～0.96,RMSEA=0.00,RMR=0.04。符合Carver量表的理论构想,具有很好的结构效度。②人类免疫缺陷病毒感染者前5位的应对方式是接受、积极应对、计划、使用工具支持和使用情感支持。③与对照组相比,人类免疫缺陷病毒感染者更多的采用否认、行为解脱和自责的应对方式(P<0.05～0.01);且在生理健康和心理健康各个方面均较对照组差(P<0.01)。④人类免疫缺陷病毒感染者的自责和行为解脱与总的生理健康和心理健康成负相关(r=-0.22～-0.44,P<0.01)。积极应对、计划和正性重构等应对方式也和反映个体生理健康的活力呈正相关(r=0.26,0.21和0.27,P<0.05)。总AIM： To explore the coping strategy and quality of life among human immunodeficiency virus （HIV）^＋ subjects infected by plasma donation. METHODS： The investigation was performed from January to July 2006. 201 HIV^＋ subjects infected by plasma donation were recruited as case group, of which 113 were diagnosed as having acquired immune deficiency syndrome （AIDS）. 200 （HIV）^- subjects, who had matched age, sex and educaton, were enro ed as control group. A subjects signed the informed consent. Carver coping strategy questionnaire and SF-36 were used for investigation. ①Carver coping strategy questionnaire included 14 subscales, and each subscale contained two items, 4-grade score, 1 as nerve, 4 as often, and total score of each subscale was 8 points. ②SF-36 included 8 dimensions. Each dimension scored by switching score, and the highest score was 100 points and the lowest score was 0 point. Total scores of physiological health and psychological health were calculated according to standard score. Verified factors and reliability of Carver coping strategy questionnaire were analyzed, and coping strategy and quality of life of the two groups were compared, and then correlation between coping strategy and quality of life in HIV^＋ subjects was analyzed. RESULTS： 430 questionnaires were sent out and 401 questionnaires with detailed content were selected with the effective rate of 93.3%. ①The Cronbach＇s α coefficients of the factors of Carver coping strategy questionnaire were from 0.55 to 0.84. The index created by confirmative factor analysis for fourteen factors model included χ^2/df=0.49, IFI=1.05, AGFI=0.93, CFI=1.00, NNFI=1.07, M1=0.44-0.96, RMSEA=0.00 and RMR=0.04. These met the ideal scheme of Carver scale and had good structural validity.②The top five coping strategies which HIV^＋ subjects applied most frequently were acceptance, active coping, planning, using emotional support and instrumental support. ③However, HIV^＋ subjects still employed more denial, Behavioral diseng

关 键 词：供血者 横断面研究 HIV感染 获得性免疫缺陷综合征 生活质量 

分 类 号：R392[医药卫生—免疫学]