口康宁漱口液治疗口腔粘膜炎的疗效研究  

A Study of Therapeutic Efficacy of Koukangning Gargle in\; the Treatment of Oral Mucositis

作　　者：曾光明[1] 李秉琦[1] 张文清[1] 林梅[1] 陈谦明[1] 

机构地区：[1]华西医科大学口腔医学院,610041

出　　处：《华西口腔医学杂志》1997年第1期28-30,共3页West China Journal of Stomatology

摘　　要：用随机法对 118例口腔粘膜炎 (复发性口疮、糜烂性扁平苔藓、疱疹性口炎、口腔粘膜血疱感染 )患者进行临床研究。试验组 5 9例 ,使用口康宁漱口液 ;对照 1组 2 9例 ,使用多贝尔氏液 ;对照 2组 30例 ,使用口泰漱口液。结果 ,口康宁组治疗 3d,6 d的显效数、总有效数明显高于多贝尔氏液组 (P<0 .0 0 5 ,P<0 .0 1,P<0 .0 0 5 ,P<0 .0 0 5 ) ,临床上亦无毒、副作用发生 ,而口康宁组与口泰组相比 ,疗效无显著性差异。实验室研究显示 ,口康宁具有抗炎作用及良好的抗菌作用 ,是一种中、西医结合的新型漱口液。A study of therapeutic efficacy was carried out in 118 patients with oral mucositis (recurrent oral aphthous ulceration, erosive lichen planus, herptic stomatitis and infectious oral mucosal hematoma) at random. As a topical medication, Koukangning gargle was applied to 59 patients of the experimental group, 29 patients of the control group 1 applied Dobell's solution to rinse their mouths, and 30 patients of the control group 2 applied Koutai solution. A satisfactory result was observed in the experimental group, its effectiveness and effective rates rose more than those of control group 1 at both treatments for 3 days and 6 days. Between the two groups, there were markedly significant difference (P<0.005, P<0.01, P<0.005, P<0.005). Koukangning gargle was nontoxic and no side effects in the clinical tests. Its efficacy was no significant difference compared with the control group 2. Experimental study demonstrates that it possesses anti inflamation effect and excellent antibiotic effect, therefore it is a new gargle for rinse mouth combined traditional Chinese medicine with Western medicine.\;

关 键 词：口康宁 漱口液 口腔粘膜炎 药物疗法 

分 类 号：R988.2[医药卫生—药品] R781.505[医药卫生—药学]