肺心病患者血清胃动素水平的变化  

The Changing Motilin Level in Plasma of Cardiopulmonary Patients

作　　者：徐鸥[1,2] 韩梅[1,2] 李艳峰[1,2] 沙丽君[1,2] 李兴文[1,2] 黄家志[1,2] 沈涛[1,2] 

机构地区：[1]昆明医学院第一附属医院呼吸内科 [2]成都军区昆明总医院全军药物依赖研究所

出　　处：《昆明医学院学报》1997年第1期20-21,25,共3页Journal of Kunming Medical College

摘　　要：采用特异的胃动素抗体，通过放射免疫测定法，测定３３例肺心病人和３０例健康人血清胃动素的含量结果发现：肺心病组胃动素含量（６８２±１３７．５）ｎｇ／Ｌ较健康组（３１６±４６．５１）ｎｇ／Ｌ升高（Ｐ＜０．０１）．且肺心病组中伴上腹饱胀、嗳气、腹泻等消化道不适者１６例胃动素为（８００±２７．３８）ｎｇ／Ｌ高于１７例无消化道不适者（６４４±１４２）ｎｇ／Ｌ（Ｐ＜０．０１）．结果表明：肺心病患者胃肠功能紊乱的因素之一与胃动素分泌异常和调节失衡有关．With specific motilin antibody and radioimmunoassay, plasma motilin level was determined in 33 cardiopulmonary patients and 30 normal subjects. As a result, average motilin level was higher ( P <0.01) in the cardiopulmonary disease group (682±137.5 ng/L) than in the healthy group (316±46.5 ng/L); and in the former, 16 gastric inadequate patients, who suffered concomitantly from epigastric repletion, belch and diarrhea, had a motilin level of 800±27.78 ng/L, higher than 644±142 ng/L of the other 17 gastric adequate patients. The results showed that for cardiopulmonary patients one factor of the gastroenternal functional disorder has a bearing on the anomaly of motilin secretion and regulation.

关 键 词：肺心病 胃动素 放射免疫测定 

分 类 号：R541.504[医药卫生—心血管疾病]