马斯平(盐酸头孢吡肟)在普胸外科围手术期防治细菌性感染的临床研究  

Clinical Study of Maxpime's Treatment to the Bacterial Infection in Thoracic Operation

作　　者：李树本[1] 何建行[1] 陈汉章[1] 韦兵[1] 殷伟强[1] 成向阳[1] 葛林虎[1] 刘君[1] 徐鑫[1] 

机构地区：[1]广州医学院第一附属医院广州呼吸疾病研究所胸外科,广东广州510120

出　　处：《海南医学》2007年第8期52-53,58,共3页Hainan Medical Journal

摘　　要：目的通过随机对照方法,观察马斯平在普胸外科围术期防治细菌性感染的有效性及安全性,并探讨其经济学效果。方法221例普胸外科手术患者,随机分为两组,围手术期分别给予马斯平和头孢他啶防治感染,观察各种感染情况,比较两组的临床效果并运用成本-效果分析法分析其经济学效果。结果实验组和对照组相比较,其防治术后感染的效果差别无显著性,而马斯平组成本-效果比低于头孢他啶组。结论普胸外科围术期应用马斯平防治细菌性感染是经济、安全和有效的。Objective To evaluate the effectiveness and economic benefits of Maxpime＇s treatment to the Bacterial Infection in Thoracic Operation. Methods 221 cases of thoracic surgical patients were randomly divided into two groups. 109 eases were treated with Maxpime and 112 cases with Ceftazidime. Clinical efficiency is compared .The economic benefits were evaluated by a pharmacoeeonomie cost-effect analysis. Results In the Maxpime group （109 patients）, the effective rate was 92.7% as compared with 90.2% of the patients in the Ceftazidime group （112 pat ients） （P〉0.05）. No significant difference was noted in both groups. The cost-effect of Maxpime was lower than that of Ceftasidime. Conclusions Application of Maxpime in perioperative period is a effective and economic prophylactic regime to prevent thoracic surgical patients from Bacterial infection.

关 键 词：马斯平 胸外科手术 围手术期 感染 

分 类 号：R619[医药卫生—外科学]