A convenient synthesis of 2-aryl substituted benzo[f][1,2,4]triazolo[1,5-a]azepine derivatives  

作　　者：Qing Qing Meng He Xiang Bai Feng Li Quan Rui Wang Feng Gang Tao 

机构地区：[1]Department of Chemistry, Fudan University, Shanghai 200433, China

出　　处：《Chinese Chemical Letters》2007年第7期785-787,共3页中国化学快报（英文版）

基　　金：carried out with the financial assistance of the National Natural Science Foundation of China （Project 20372015）.

摘　　要：A convenient synthetic pathway to 2-aryl-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[1,5-a]azepine derivatives 7 was developed.The synthesis was based on the cycloaddition of the 1,2,3,4-tetrahydronaphthalene α-acetoxy azo compounds 3 with Ar-CN in the presence of AlCl3 and the consecutive ring enlargement.A convenient synthetic pathway to 2-aryl-5,6-dihydro-4H-benzo[f][1,2,4]triazolo[1,5-a]azepine derivatives 7 was developed.The synthesis was based on the cycloaddition of the 1,2,3,4-tetrahydronaphthalene α-acetoxy azo compounds 3 with Ar-CN in the presence of AlCl3 and the consecutive ring enlargement.

关 键 词：Benzotriazoloazepine NITRILES 1 3-Dipolar cycloaddition Ring expansion 

分 类 号：O626.26[理学—有机化学]