Design, synthesis and in vitro evaluation of phenylbenzamidine derivatives as SSRIs  

作　　者：Jing Yang Xiaofang Wang Hui Wen Fang Qin Guang Zhong Yang 

机构地区：[1]Institute of Materia Medica, Peking Union Medical College and Chinese Academy of Medical Science, Beijing 100050, China

出　　处：《Chinese Chemical Letters》2007年第7期814-816,共3页中国化学快报（英文版）

基　　金：the National Natural Science Foundation of China （No. 30572233） ;Beijing Natural Science Foundation （No. 7062045）.

摘　　要：A series of phenylbenzamidine analogs were synthesized and tested for their biological activities of inhibiting the reuptake of 5-HT. All of them were new compounds, and their structures were confirmed by 1HNMR, MS and XRD.A series of phenylbenzamidine analogs were synthesized and tested for their biological activities of inhibiting the reuptake of 5-HT. All of them were new compounds, and their structures were confirmed by 1HNMR, MS and XRD.

关 键 词：SSRIS Phenylbenzamidine XRD 

分 类 号：O625.1[理学—有机化学]